Anthony Didato, DMD Balanced Aesthetics + Wellness 90% of Serotonin Produced in the Gut Approximately 90% of the body's serotonin the neurotransmitter most associated with mood regulation is produced by enterochromaffin cells Cell (Yano et al., 2015) Gut-Brain Axis Bidirectional Communication The gut-brain axis describes bidirectional signaling between the enteric nervous system and central nervous system via the vagus nerve, immune Annals of Gastroenterology Leaky Gut (Intestinal Permeability) and Systemic Inflammation Increased intestinal permeability allows endotoxins (LPS) to enter the bloodstream, triggering systemic inflammatory cascades linked to anxiety, depression, brain fog, Frontiers in Immunology Overnight Fasting Improves Microbial Balance A 12-14 hour overnight fast improves microbial balance and insulin sensitivity
By targeting NNMT and supporting NAD+ levels, it addresses cellular energy metabolism rather than manipulating appetite or stimulating the nervous system
The mechanism of catalpol in protecting -cell functionand improving hepatic insulin resistance
It is reported that these GSTs subtypes are involved in the development of DM and its complications [5], so it is important to understand the impact of these oxidative changes and the possible effects of genetic polymorphisms of GSTs in diabetic patients [6]
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And the idea of getting poked in the head and neck every 12 weeks might sound like a hard pass